Triple-negative breast cancer (TNBC) is tough to treat. It doesn't respond well to common therapies. But why? Recent research points to fat cells nearby. These fat cells change in ways that help cancer grow and spread. Normally, fat cells store energy. But in TNBC, they lose fat and become inflamed. This isn't good. The changed fat cells send signals to cancer cells...
Stomach cancer is a serious illness. It gets even trickier when it spreads to other parts of the body. This spreading, known as metastasis, makes treatment tough and affects how well patients do. Doctors and researchers are keen to understand how and where the cancer spreads. This knowledge can help them create better treatment plans and predict how patients will far...
Gastric cancer is a big deal. It's one of the most common cancers affecting the digestive system. Once it spreads, things get really tough. This is where a small protein called FNDC3B comes into play. It's a tiny helper that's been spotted in various tumors. But its role in stomach cancer? That's been a bit of a mystery until now. The big question is: How do...
The spread of colorectal cancer to the liver is a big problem. It often comes back after surgery. This might be because some cancer cells stick around and start growing again. These cells can be influenced by other factors in the body. Tumor-associated macrophages, or TAMs, are a type of immune cell. They are found in high numbers where cancer has spread to the live...
A new study has shaken up the way doctors might approach tongue cancer. It has uncovered a simple yet powerful tool for predicting how aggressive the cancer might be. The key? The ratio of the tumor's width to the tongue's width. This ratio could help doctors figure out if the cancer has spread to the lymph nodes in the neck. This is a big deal because knowing t...
Thyroid cancer is often seen as a manageable condition. But for those who face distant metastasis, the journey is far from easy. Distant metastasis means cancer has spread to other parts of the body. This can lead to serious physical and emotional hurdles. To shed light on these challenges, a study focused on the experiences of thyroid cancer survivors dealing with d...
There is a protein called TAK1. It plays a big role in many cell activities. But its part in cancer spread is not fully known. Researchers have found that when TAK1 is reduced, a type of throat cancer, called esophageal squamous cancer, spreads faster. This happens both in lab dishes and in live mice. So, TAK1 seems to slow down cancer spread. Now, let's talk about ...
Stomach cancer is a serious health issue. It can spread to the lining of the abdomen. This is known as peritoneal metastasis. Doctors have been testing a treatment called intraperitoneal chemotherapy. This is a type of chemo that goes directly into the belly. It sounds promising, but how well does it work? A recent study looked at many past studies. It tried to find ...
Cancer cells are sneaky. They find ways to sneak into blood vessels, and this is how they spread. This process is called intravasation. It's tricky to study because it's hard to recreate in a lab. But now, there's a new tool called INVADE. It's a tiny, clever device that mimics how blood vessels work. It has 23 little chambers, each with a fake blood vessel lining. T...
Peritoneal metastasis is a tough nut to crack. It's hard to treat with standard immunotherapy. The reason? The body's own defenses are weakened in the abdomen, and there's a barrier that stops treatments from working properly. But there's a new player in town: sonodynamic therapy. It's a fancy name for a simple idea. Use sound waves to fight cancer. This therapy has ...