Scientists are always looking for better ways to make medicines last longer and work better. One big challenge is keeping proteins, like those in some drugs, stable when they are dried out. Trehalose is a sugar that is often used to help protect these proteins. But there's a problem: trehalose can change form when it gets hot or humid, which can mess up the proteins ...

Protein stability is a big deal in biology. Scientists need to know how proteins behave when heated, but traditional methods can be slow and expensive. Enter the new kid on the block: a microplate-based approach to intrinsic differential scanning fluorimetry (DSF). This method can test up to 384 samples at once, using just a tiny amount of each sample—only 10 microli...

Biocatalysis is all about using enzymes to make stuff, and it's a big deal for many industries. One cool way scientists are making it even better is by looking back in time. They use something called ancestral sequence reconstruction (ASR) to figure out what ancient enzymes might have looked like. This helps them create super-stable enzymes and even tools to make new...