The study looks at how adding phosphate groups to a protein called p16INK4a affects its grip on another protein, CDK4. The two proteins normally team up to stop cells from dividing too fast. Scientists used computer simulations that track every atom in the molecules to see what happens when specific
The Securities and Exchange Commission (SEC) once boasted about tackling crypto fraud with 583 cases and $8. 2 billion in penalties last year, claiming it stayed ahead of new threats. That image has shifted dramatically. In a fresh review for 2025, the agency admits it over‑reacted and pulls back on
The week started with a shock: Melania Trump, usually silent about politics, stepped forward to deny ties with Jeffrey Epstein and called for a hearing on his victims. Her words came out of nowhere, sparking speculation that she might be trying to protect her husband’s image or to signal a new stanc
The way governments decide which new medicines to fund usually looks only at the total health improvement they bring. Who gets those benefits and how that affects wealth gaps is rarely considered. In the Netherlands, researchers asked ordinary people to weigh in on this question. They used a techni
The University of Alabama’s spring scrimmage offered plenty to cheer about. A redshirt freshman quarterback threw four touchdown passes, and the defense made a strong impression. The kicker hit two long field goals, while the running game showed promise. After the game, head coach Kalen DeBoer answ
The state’s health insurance landmark will be highlighted on Monday at Boston’s historic Faneuil Hall, where former governors and current leaders gather to mark twenty years since the 2006 law that brought coverage to nearly all residents. The gathering will feature speeches from Gov. Maura Healey a
The state’s mental‑health diversion plan, created in 2018 to keep people with serious illnesses out of jail, is under fire from prosecutors who say it lets dangerous offenders slip through the cracks. A high‑profile case that fuels this debate involved a man who was allowed to live in an LA shelt
The risk of cancer spreading into the seminal vesicles can be spotted before a radical prostatectomy by looking at several warning signs. One major factor is the cancer’s size; tumors that are larger tend to reach nearby tissues more easily. When the tumor’s edge touches or goes beyond the prostate
The new education secretary, who once ran a family business in professional wrestling, is set to speak at Yale this Thursday. The event, hosted by a conservative think‑tank that often invites speakers to Ivy League campuses, promises a “roadmap” for changing how schools are run. Critics say the plan
The first Monday of April in Geneseo feels like a clear, chilly morning. A visitor steps into Sweet Arts Bakery, removes thick gloves, and chats with the baker about a forecast that promises snow for the next day. The idea sparks: even though the sky is gray, a high school field might soon host a ga
